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 CombiFlash® Rf

RFID method automation, more fractions, larger screen, higher pressure – all in a smaller package.

Teledyne Isco advances automated chromatography again with the CombiFlash Rf system. The CombiFlash Rf uses RFID (Radio Frequency Identification) technology to automate setting the parameters for purification runs and fraction collection.

The CombiFlash Rf has built-in solvent and waste management that prevent columns from drying, and messy waste overfills. A new automated valve lets you load samples and walk away – and it's self-cleaning to wash away materials that can contaminate the next run.

The CombiFlash Rf improves your productivity whether you separate synthetic compounds, natural products, peptides, polymers, or other chemical separations.

Standard Features

• Space saving design is smaller than other flash chromatography systems on the market, freeing scarce hood space for other uses.
  
• Solvent and waste management prevents columns from drying and waste containers from hazardous overflows.
  
• Large touch screen 10.5" (26.7 cm) puts the most used controls on a single, easy to read display.
  
• Large fraction capacity allows longer runs without changing racks. You don't need to divert time from other activities to watch your purification.
  
• RFID (Radio Frequency Identification) identifies columns and loads the appropriate method for the best separation. With reusable bonded-phase columns, the system tracks the number of runs on the column as well as the last solvent used, so you know whether you need to flush the column.
  
• RFID identification of fraction collection racks sets the maximum fraction size to prevent overflows.
  
• Injection valve features wide bore, straight plumbing, and self-cleaning to prevent clogs that cause down-time.
  
• No waiting to access data - networking allows lets you connect to the CombiFlash® Rf to monitor and remotely control your experiment, analyze data, and print to network printers.
  
• Rapid column air purge prevents solvent from being discarded with the used column. It is better for the environment, safer in the lab, and eliminates messy column removal.
  
• TLC Rf to Gradient calculator determines optimal separation parameters while minimizing run time.
  
• Easy scale-up with built-in method-scaling means you won’t need to re-develop your method. You save time when you increase reaction size. You can even scale up to a 1500g column run on a Companion XL.
  
• Back pressures to 200 psi for improved separations.
  
• One-year parts and labor warranty.

Options and Accessories

• 13 x 100 mm tube racks, qty 2 (108 tubes/rack), 60-5237-013
  
• 16 x 125 mm tube racks, qty 2 (75 tubes/rack), 60-5237-031
  
• 16 x 150 mm tube racks, qty 2 (75 tubes/rack), 60-5237-032
  
• 18 x 150 mm tube racks, qty 2 (70 tubes/rack), 60-5237-033
  
• 18 x 180 mm tube racks, qty 2 (70 tubes/rack), 60-5237-034
  
• 25 x 150 mm tube racks, qty 2 (30 tubes/rack), 60-5237-035
  
• 480 ml French square bottle, qty 1 rack for 12 bottles. 60-5237-040
  
• 20 ml (28 x 61 mm) scintillation vial tube racks, qty 2 (27 vials/rack), 60-5394-469
  
• 40 ml (28 x 95 mm) scintillation vial tube racks, qty 2 (30 vials/rack), 60-5394-468
  
• Adjustable Solid Load Cartridge Caps (SLCC), 5 gram, 25 gram, and 65 gram
  
• RediSep Rf prepacked columns
  
• Sample load prepacked, silica gel cartridges
  
• Sample load, empty cartridge
  
• UV-vis PDA detector (200 -780 nm), internal
  
• Model 340CF Evaporative Light Scattering Detection (ELSD) module, external

Specifications

CombiFlash® Rf
Controller:	10.5" touchscreen (26.7 cm), or external web browser via ethernet. Data and current run can be accessed by up to 10 remote computers. Front panel USB port to save data and transfer files.
PeakTrak software for:	One-screen method development; Real-time control - change method parameters during a run without pausing; Converting Rf values into solvent gradients; Method scaling -transfer method from one size column to another, from 4g to 330g; Converting methods to 750g and 1500g columns on Companion XL; Color-coded fraction identification.
Programmable gradients:	Linear and/or step gradients. Change profiles anytime during run, using "Click and drag" gradients. Pause gradient for isocratic hold.
Pumping system:	Positive displacement pumps. 5-200 ml/min. 0-200 psi (when used with RediSep Rf columns)
Gradients:	Four solvent, binary; Accuracy < 1% full scale
Column sizes:	4g to 330g.
Fraction collection:	Internal fraction collector capacity- 13x100 mm tubes - 216, 16x125/150 mm tubes - 150, 18x150/180 mm tubes - 140, 25x150 mm tubes - 60, 40 ml scintillation vials - 60, 20 ml scintillation vials - 54, 480 ml bottles - 12.
Fraction Size:	Determined by peak cutting and by user-defined maximum tube volume
Sample injection:	Autoinject with 6-position motor powered sample loading valve; self-cleans at end of run; solid or liquid injection
Detection:	UV variable dual-wavelength, software selectable, 200-360nm. Slope and threshold peak detection. Detector range: 0.2-3.0 AUFS. Display of peak purity by 2 wavelength ratio.
Safety:	Static dissipating tubing, vapor sensor, and column air purge.
Sample security:	Auto-run extension at end of run, and over pressure sensor.
Solvent management:	Four solvent and one waste fluid level monitoring
Dimensions (W x D x H):	14.1 x 17 x 24 inches, (35.8 x 43.2 x 61.0 cm)
Weight:	54 lbs. (24.5 kg)
Certifications:	CE and CSA