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 NEW! CombiFlash® Rf 4x

Four-channel, walk-away automation

Multitask like never before with the CombiFlash Rf 4x system, a four-sample automated version of the innovative CombiFlash Rf personal purification system. Its built-in control system acts as an Internet server, generating a web page that can be viewed using a touch screen, desktop or laptop computer running Microsoft® Internet Explorer®. You and your colleagues can monitor progress and schedule your time more productively.

The CombiFlash Rf 4x system uses precision-packed RediSep® Rf columns from 4 grams to 330 grams, which are quickly interchangeable with no additional hardware — saving you time and money. You can also use multiple column sizes and various stationary phases in one batch. Enjoy fast, easy scale-up from milligrams to tens of grams of purified sample.

Standard Features

• Sense remaining solvent volume in supply bottles with optional solvent management module.
  
• Multi-sample automation lets you share resources with other chemists, without waiting in line.
  
• Different size columns (4 grams to 330 grams) can be used for each channel.
  
• RFID column sensing automatically programs optimal parameters for each sample channel; channels can also run with customized parameters.
  
• Up to 200 psi operating pressure – ideal for reversed phase Flash chromatography.
  
• Delivers four times the productivity in less than nine inches of linear bench space.
  
• Increase work efficiency with multiple columns – load and program new runs without interrupting the purification in progress.
  
• Sample automation lets you share resources with other chemists, without waiting in line.
  
• An optional post-run air purge can clear solvent from all columns before disposal.
  
• Automatic, self-cleaning valve allows unattended operation and minimizes cross-contamination.
  
• The system can deliver waste fluids from each channel to independent containers and can monitor the fluid level in each to prevent over-filling.
  
• Convert from normal to reversed phase conditions in minutes.

Applications

• Drug discovery
  
• Agrochemistry
  
• Petrochemistry
  
• Quick scale up of intermediate compounds from milligram to several grams

Options and Accessories

• RediSep Rf prepacked columns
  
• Sample load prepacked cartridges
  
• Sample load, empty cartridges

Specifications

Channels:	4
Pumping system:	Two positive displacement pumps (located in CombiFlash Rf)
Gradients:	Four solvent, binary; Accuracy<1% full scale
Gradient formation options:	Linear, step, isocratic gradients. Change profiles any time during run.
Flow rate:	5 to 200 ml/min
RediSep Rf column sizes:	4g to 330g
Maximum pressure:	200 psi (13.8 bar)
Detection:	UV variable, 200-360 nm. User-selectable wavelength. For threshold and/or peak detection; user-selectable monitor wavelength for compound purity.
Fraction collection:	108 tube capacity, unlimited rack changes
Optional tube sizes:	Racks available for 12/13, 16, 18, and 25 mm tubes, 480 ml bottles, and other containers
Sample injection:	Automated, self-cleaning 6-position valves for solid and liquid injections
Waste outlets:	Waste fluids isolated by channel, with level sensing.
Power options:	100/117 VAC, 50/60 Hz; 234 VAC, 50/60 Hz
4x module dimensions (H x W x D):	22.6 x 24 x 17 inches; 57.4 x 61 x 43.2 cm
CombiFlash Rf 4X weight:	90 lbs; 40.8 kg
4x module dimensions (H x W x D):	8.5 x 24 x 17 inches; 21.6 x 61 x 43.2 cm
4X module weight:	30 lbs; 13.6 kg