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 CombiFlash® Companion® 4x

Companion's advanced control and ease of operation – with multi-sample automation (discontinued)

Set up your samples and walk away!

You'll multitask like never before with the Companion 4x, a four-sample automated version of the innovative CombiFlash Companion personal purification system. Its built-in control system acts as an Internet server, generating a web page that can be viewed using a touch screen,desktop or laptop computer running Microsoft® Windows® Explorer. You and your colleagues can monitor progress and schedule your time more productively.

Different columns for different samples

Companion 4x uses precision-packed RediSep® Rf columns from 4 grams to 330 grams, which are quickly interchangeable with no additional hardware—saving you time and money. You can also use multiple column sizes and various stationary phases in one batch. Enjoy fast, easy scale-up from milligrams to tens of grams of purified sample.

Standard Features

• Convert from normal to reversed phase conditions in minutes. Change solvents rapidly with the optional solvent management module.
  
• Sense remaining solvent volume in supply bottles with optional solvent management module.
  
• Multi-sample automation lets you share resources with other chemists, without waiting in line.
  
• Increase work efficiency with multiple columns—load and program new runs without interrupting the purification in progress.
  
• Companion 4x purifies four samples unattended and e-mails the results to you.
  
• Different size columns (4 grams to 330 grams) can be used for each channel.
  
• Column sensing automatically programs optimal parameters for each sample channel; channels can also run with customized parameters.

Applications

• Drug discovery
  
• Agrochemistry
  
• Petrochemistry
  
• Quick scale up of intermediate compounds from milligram to several grams

Options and Accessories

• Solvent Management Module – controls up to 4 solvents on line, solvent reservoir level sensing
  
• External Foxy Jr. fraction collector for increased tube capacity
  
• Foxy collection racks for additional tube sizes
  
• RediSep Rf prepacked columns
  
• Sample load prepacked, silica gel cartridges
  
• Sample load, empty cartridges

Specifications

CombiFlash Companion 4x
Samples per run:	4
Solvent delivery:	Two maintenance-free, valveless metering pumps
Safety certification:	CE
Programmable gradients:	2 solvent isocratic, linear and/or step gradients; optional 4-solvent capability
Flow rate:	5 to 100 ml/min
RediSep Rf column sizes:	4g to 330g
Rated pressure:	50 psi (3.5 bar)
Liquid sample loading:	Injection valve to load column directly
Solid sample loading:	Solid load cartridge for low-solubility samples
On-line UV detection:	Photodiode array absorbance detector (200 - 360 nm)
Fraction collection:	Foxy fraction collector with 144 tube capacity, unlimited rack changes, optional 288 tube capacity
Optional tube sizes:	Racks available for 12, 13, 16, 18, & 25 mm tubes, 480 ml bottles, and other containers
Power options:	100/117 VAC, 50/60 Hz; 234 VAC, 50/60 Hz
Companion dimensions (HxWxD):	49 x 49 x 54cm
Companion weight:	27.2 kg
4x module dimensions (HxWxD):	49 x 30 x 34cm
4x weight:	13 kg
Total weight:	40.2 kg
Solvent reservoir level sensing:	optional